On the Wireless Microwave Sensing of Bacterial Membrane Potential in Microfluidic-Actuated Platforms

On the Wireless Microwave Sensing of Bacterial Membrane Potential in Microfluidic-Actuated Platforms

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On the Wireless Microwave Sensing of Bacterial Membrane Potential in Microfluidic-Actuated Platforms

Version 1
: Received: 27 February 2021 / Approved: 2 March 2021 / Online: 2 March 2021 (11:24:18 CET)

How to cite:
Jofre, M.; Jofre, L.; Jofre-Roca, L. On the Wireless Microwave Sensing of Bacterial Membrane Potential in Microfluidic-Actuated Platforms. Preprints 2021, 2021030079 (doi: 10.20944/preprints202103.0079.v1).

Jofre, M.; Jofre, L.; Jofre-Roca, L. On the Wireless Microwave Sensing of Bacterial Membrane Potential in Microfluidic-Actuated Platforms. Preprints 2021, 2021030079 (doi: 10.20944/preprints202103.0079.v1).

Cite as:

The investigation of the electromagnetic properties of biological particles in microfluidic platforms may enable wireless monitoring and interaction with functional activity of microorganisms. Of high relevance is the membrane potential as it is one of the most important parameters of living cells. In particular, the complex mechanisms of the cell’s membrane potential are comparable to the dynamics of bacteria membranes, providing a simplified platform for advancing the current techniques and knowledge of general bio-particle dynamics. In this work, we provide a theoretical analysis and experimental results on the microwave detection of bacteria on a microfluidic-based framework for sensing the membrane potential of bacteria. The results enable to further advance the state-of-the-art of electromagnetic bacteria sensing and microfluidic control, and their implication for measuring and interacting with the cell and its membrane potentials, which is of great importance for developing new biotechnological engineered systems and solutions.

Subject Areas

Bacteria; elasto-inertial focusing; microfluidics; microwaves; membrane potential; sensing; shear stress; single cell detection; system-on-a-chip

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